Monday, 22 October 2012

Medical Breakthrough- Diabetes genes identified?

As I was scouring the NHS website, I came across a medical article discussing the perhaps identification of a diabetes gene. Link to the article below:

NHS Diabetes Article

A little bit of background knowledge on type 2 diabetes:

Type 2 diabetes occurs when the body doesn't produce enough insulin to function properly, or the body’s cells don't react to insulin. This is known as insulin resistance.
Type 2 diabetes is far more common than type 1 diabetes, which occurs when the body doesn't produce any insulin at all. In the UK, about 90% of all adults with diabetes have type 2 diabetes.

The article discusses the implications of perhaps identifying the gene in our DNA that determines the likelihood of a person developing diabetes. The investigation consisted a total of 150,000 people. 35,000 of these people had type 2 diabetes, where as 115,000 people were without the condition. As a result, the researchers found a whole of 10 new common genetic variations associated with an increase of 7-13% in a person's odds of developing type 2 diabetes. The researchers would look at something as minute as specific single letter differences.

A big factor that we need to consider is that not just genetic but also environmental factors can influence a person's odds of developing the condition. E.g. Diet and physical factors.
In conclusion, the researchers have gained a great deal of understanding of the complexity of diabetes and the researchers have identified a number of genes near to these variations that may be responsible for the condition.

As a result of the complexities of the condition, much more research will be needed to see if these results can be translated into successful treatments.

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